Leicester City's Kelechi Iheanacho scored two poacher's goals as they beat Manchester United 3-1 in their FA Cup quarter-final on Sunday to set up a last-four clash against Southampton.
With Liverpool still to visit Chelsea, who trail them by nine points with two games in hand, Juergen Klopp's side may have to beat Brighton & Hove Albion on May 13 and rely on their superior goal difference to qualify for the Champions League, assuming they do not secure it by winning this year's trophy.
Substitute Jesse Lingard struck twice in the second half as Manchester United fought back from 2-0 down to earn a 2-2 Premier League draw with Burnley at Old Trafford on Tuesday.
Chelsea were given a stiff examination by Stoke City at Stamford Bridge on Saturday before extending their lead at the top of the Premier League.
News of all that's transpired on and off the football field
Arsenal slumped to a last-gasp 2-1 Premier League defeat at relegation-threatened Brighton & Hove Albion on Saturday in a blow to the London club's chances of securing European football next season. Watford's Craig Dawson grabbed a stoppage-time equaliser with an overhead kick to earn his side a 1-1 draw with Leicester City on Saturday and a vital point in their battle for Premier League survival.
Imperious Liverpool extended their Premier League home winning streak against Arsenal to six on Saturday with an easy 4-0 victory that lifted them to second in the table.
Photos from the Champions League matches played across Europe on Tuesday
Manchester City's Sergio Aguero scored a hat-trick as coach Pep Guardiola maintained his 100 per cent record at the club with a commanding 4-0 victory against Borussia Moenchengladbach in their rearranged Champions League Group C opener on Wednesday.